diff --git a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/CHANGELOG.md b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/CHANGELOG.md
index 7d0c08c67eec..da959d33c89e 100644
--- a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/CHANGELOG.md
+++ b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/CHANGELOG.md
@@ -8,6 +8,9 @@
 
 ### Bugs Fixed
 
+* Always set Dependency.Target to "server.address" and "server.port" if present.
+  ([#48317](https://github.com/Azure/azure-sdk-for-net/pull/48317))
+
 ### Other Changes
 
 ## 1.4.0-beta.2 (2024-10-11)
diff --git a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Customizations/Models/RemoteDependencyData.cs b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Customizations/Models/RemoteDependencyData.cs
index 3c6767fad2e4..d09c636d9ed3 100644
--- a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Customizations/Models/RemoteDependencyData.cs
+++ b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Customizations/Models/RemoteDependencyData.cs
@@ -3,7 +3,6 @@
 
 using System.Diagnostics;
 using System.Globalization;
-using Azure.Core;
 using Azure.Monitor.OpenTelemetry.Exporter.Internals;
 
 namespace Azure.Monitor.OpenTelemetry.Exporter.Models
@@ -34,6 +33,9 @@ public RemoteDependencyData(int version, Activity activity, ref ActivityTagsProc
                 case OperationType.Messaging:
                     SetMessagingDependencyProperties(activity, ref activityTagsProcessor.MappedTags);
                     break;
+                default:
+                    Target = activityTagsProcessor.MappedTags.GetTargetUsingServerAddressAndPort();
+                    break;
             }
 
             dependencyName ??= activity.DisplayName;
diff --git a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Internals/AzMonListExtensions.cs b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Internals/AzMonListExtensions.cs
index 90c60104ac8a..132777870ce7 100644
--- a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Internals/AzMonListExtensions.cs
+++ b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/src/Internals/AzMonListExtensions.cs
@@ -261,6 +261,24 @@ internal static string GetDefaultDbPort(string? dbSystem)
             return target;
         }
 
+        [MethodImpl(MethodImplOptions.AggressiveInlining)]
+        internal static string? GetTargetUsingServerAddressAndPort(this AzMonList tagObjects)
+        {
+            var serverAttributes = AzMonList.GetTagValues(ref tagObjects, SemanticConventions.AttributeServerAddress, SemanticConventions.AttributeServerPort);
+
+            var serverAddress = serverAttributes[0]?.ToString();
+            if (!string.IsNullOrEmpty(serverAddress))
+            {
+                var serverPort = serverAttributes[1]?.ToString();
+
+                return string.IsNullOrEmpty(serverPort)
+                    ? serverAddress
+                    : serverAddress + ":" + serverPort;
+            }
+
+            return null;
+        }
+
         ///<summary>
         /// Gets Http dependency target from activity tag objects.
         ///</summary>
diff --git a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/tests/Azure.Monitor.OpenTelemetry.Exporter.Tests/RemoteDependencyDataTests.cs b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/tests/Azure.Monitor.OpenTelemetry.Exporter.Tests/RemoteDependencyDataTests.cs
index ed218ba86c6c..f2108aa0af22 100644
--- a/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/tests/Azure.Monitor.OpenTelemetry.Exporter.Tests/RemoteDependencyDataTests.cs
+++ b/sdk/monitor/Azure.Monitor.OpenTelemetry.Exporter/tests/Azure.Monitor.OpenTelemetry.Exporter.Tests/RemoteDependencyDataTests.cs
@@ -190,5 +190,46 @@ public void HttpDependencyNameIsActivityDisplayNameByDefault()
 
             Assert.Equal(activity.DisplayName, remoteDependencyDataName);
         }
+
+        [Fact]
+        public void VerifyAllDependenciesSetTargetViaServerAddress()
+        {
+            using ActivitySource activitySource = new ActivitySource(ActivitySourceName);
+            using var activity = activitySource.StartActivity(
+                ActivityName,
+                ActivityKind.Client,
+                parentContext: new ActivityContext(ActivityTraceId.CreateRandom(), ActivitySpanId.CreateRandom(), ActivityTraceFlags.Recorded),
+                startTime: DateTime.UtcNow);
+
+            Assert.NotNull(activity);
+            activity.SetTag(SemanticConventions.AttributeServerAddress, "unitTestAddress");
+
+            var activityTagsProcessor = TraceHelper.EnumerateActivityTags(activity);
+
+            var remoteDependencyData = new RemoteDependencyData(2, activity, ref activityTagsProcessor);
+
+            Assert.Equal("unitTestAddress", remoteDependencyData.Target);
+        }
+
+        [Fact]
+        public void VerifyAllDependenciesSetTargetViaServerAddressAndPort()
+        {
+            using ActivitySource activitySource = new ActivitySource(ActivitySourceName);
+            using var activity = activitySource.StartActivity(
+                ActivityName,
+                ActivityKind.Client,
+                parentContext: new ActivityContext(ActivityTraceId.CreateRandom(), ActivitySpanId.CreateRandom(), ActivityTraceFlags.Recorded),
+                startTime: DateTime.UtcNow);
+
+            Assert.NotNull(activity);
+            activity.SetTag(SemanticConventions.AttributeServerAddress, "unitTestAddress");
+            activity.SetTag(SemanticConventions.AttributeServerPort, "unitTestPort");
+
+            var activityTagsProcessor = TraceHelper.EnumerateActivityTags(activity);
+
+            var remoteDependencyData = new RemoteDependencyData(2, activity, ref activityTagsProcessor);
+
+            Assert.Equal("unitTestAddress:unitTestPort", remoteDependencyData.Target);
+        }
     }
 }