VEP's COSMIC annotations - terms and conditions

[sigven]

Hi,

I have noticed COSMIC's new licensing policies, where terms are strict and most usage falls under "Commercial Use". Since VEP can provide COSMIC identifiers (position-specific, not allele-specific) as part of its annotation output, I was curious how COSMIC considers the use of VEP for this purpose, considering e.g. the case in which VEP is integrated and part of a publicly available academic tool.

I asked the following question to the COSMIC team:

Variant Effect Predictor (VEP) is an academic tool that can provide links to
COSMIC for variants found here (position-specific, not allele specific match) -
is it so that if one integrates VEP in a service/report, this falls underneath
Commercial Use? Meaning if one is to use VEP for clinical reporting without a
Commercial license, one needs to turn off this functionality/output?

This was the response I got from COSMIC:

If you integrate the tool you are essentially integrating COSMIC data and so
yes my understanding would be that a clinical license would be required for
this.

Do you have any comments on this matter, meaning how to use VEP and stick to non-Commercial Use (wrt COSMIC)?

kind regards,
Sigve

[nakib103]

Hi @sigven,

Thanks for your query!

We have an agreement with COSMIC to publish the minimal amount of data we currently publish (COSMIC ids with position match). There is a discussion going on with the COSMIC team about how the new terms and condition apply to us. Once we have a clear understanding, we can clarify this matter to you.

Kind regards,
Nakib

[sigven]

OK, great, thanks for the update!

[sigven]

Hi,

Are there any updates on VEP’s COSMIC annotations?

Kind regards,
Sigve

[nakib103]

Hi @sigven, unfortunately we do not have any update regarding this issue.

[sigven]

Ok, thanks for the response.