task_designs

Task designs

Task design *.mat file is used as an input for TMFC simulations using Python code.

The output of the Python code is simulated BOLD time series *.mat file.

Task design and simulated BOLD time series *.mat files are used as input for TMFC analysis using MATLAB code.

"Task design" data structures

• durations{1,i} - durations of blocks/events for i-th condition
• names{1,i} - name for i-th condition
• onsets{1,i} - stimulus onset times for i-th condition
• rest_matrix{1,1} - weighting factors [k x k] for the construction of synaptic weight matrices (k - number of functional modules in the network)
• task_matrices{1,i} - weighting factors [k x k] for the construction of synaptic weight matrices for i-th condition (k - number of functional modules in the network)
• activations{1,i} - indicate which functional modules are activated during i-th condition (activations are modelled by simple box-car functions)
  • for example, consider 4 functonal modules, modules 1 & 3 activated during Cond№1, modules 2 & 4 activated during Cond№2
  • activations{1,1} = [1 0 1 0]
  • activations{1,2} = [0 1 0 1]

Onsets, durations and condition names are defined in the same way as for multiple conditions *.mat file for SPM12.

Experiments:

• 01_BLOCK [2s_TR] [20s_DUR] [10_BLOCKS]

  • Block design
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 10 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 13.3 min

• 02_EVENT [2s_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Default event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 23.6 min

• 03_EVENT [500ms_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 500 ms
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 14 time points (7 s)
  • Total scan time = 23.6 min

• 04_EVENT [700ms_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 700 ms
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 10 time points (7 s)
  • Total scan time = 23.6 min

• 05_EVENT [1s_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 1 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 6 time points (6 s)
  • Total scan time = 23.6 min

• 06_EVENT [3s_TR] [1s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 3 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (9 s)
  • Total scan time = 23.6 min

• 07_EVENT [2s_TR] [100ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 20.6 min

• 08_EVENT [2s_TR] [250ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 250 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 21.1 min

• 09_EVENT [2s_TR] [500ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 500 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 22 min

• 10_EVENT [2s_TR] [2s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 2 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 27 min

• 11_EVENT [2s_TR] [4s_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 4 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 33.8 min

• 12_EVENT [2s_TR] [1s_DUR] [2s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 1-3 s (mean ISI = 2 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 10.4 min

• 13_EVENT [2s_TR] [1s_DUR] [4s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 2-6 s (mean ISI = 4 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 17 min

• 14_EVENT [2s_TR] [1s_DUR] [8s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 6-10 s (mean ISI = 8 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 30.4 min

• 15_EVENT [2s_TR] [1s_DUR] [12s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 10-14 s (mean ISI = 12 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 44 min

• 16_EVENT [2s_TR] [1s_DUR] [6s_ISI] [20_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 20 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 5 min

• 17_EVENT [2s_TR] [1s_DUR] [6s_ISI] [40_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 40 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 9.7 min

• 18_EVENT [2s_TR] [1s_DUR] [6s_ISI] [60_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 60 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 14 min

• 19_EVENT [2s_TR] [1s_DUR] [6s_ISI] [80_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 80 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 19 min

• 20_EVENT [2s_TR] [100ms_DUR] [6s_ISI] [200_TRIALS]

  • Event-related design
  • TR = 2 s
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 200 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 40.9 min

• 21_EVENT [500ms_TR] [100ms_DUR] [6s_ISI] [50_TRIALS]

  • Event-related design
  • TR = 500 ms
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 50 events per condition
  • Dummy scans: first 14 time points (7 s)
  • Total scan time = 10.3 min

• 22_EVENT [700ms_TR] [100ms_DUR] [6s_ISI] [70_TRIALS]

  • Event-related design
  • TR = 700 ms
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 70 events per condition
  • Dummy scans: first 10 time points (7 s)
  • Total scan time = 14.4 min

• 23_EVENT [1s_TR] [100ms_DUR] [6s_ISI] [100_TRIALS]

  • Event-related design
  • TR = 1 s
  • Event duration = 100 ms
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 6 time points (6 s)
  • Total scan time = 20.6 min

• 24_BLOCK [2s_TR] [20s_DUR] [10_BLOCKS] [ASYMMETRIC]

  • Block design
  • Asymmetric synaptic weight matrices
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 10 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 13.3 min

• 25_BLOCK [2s_TR] [20s_DUR] [20_BLOCKS] [ASYMMETRIC]

  • Block design
  • Asymmetric synaptic weight matrices
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 20 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 26.6 min

• 26_EVENT [2s_TR] [1s_DUR] [6s_ISI] [100_TRIALS] [ASYMMETRIC]

  • Event-related design
  • Asymmetric synaptic weight matrices
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 100 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 23.6 min

• 27_EVENT [2s_TR] [1s_DUR] [6s_ISI] [200_TRIALS] [ASYMMETRIC]

  • Event-related design
  • Asymmetric synaptic weight matrices
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI) = 4-8 s (mean ISI = 6 s)
  • 200 events per condition
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 40.9 min

• 28_BLOCK [720ms_TR] [HCP_WM]

  • Block design (Human Connectome Project, Working Memory Task)
  • Repetition time (TR) = 720 ms
  • Task block duration = 27.5 s (2-back, 1-back)
  • Rest (R) = 15 s
  • 8 blocks per condition
  • Block sequence: [2-b, 1-b, R, 2-b, 1-b, R, 2-b, 2-b, R, 1-b, 1-b, R, 2-b, 1-b, R, 2-b, 1-b, R, 1-b, 2-b, R, 1-b, 2-b]
  • Dummy scans: first 25 time points (18 s)
  • Total scan time = 10 min

• 29_BLOCK [720ms_TR] [HCP_SOCIAL]

  • Block design (Human Connectome Project, Social Cognition Task)
  • Repetition time (TR) = 720 ms
  • Task block duration = 23 s (Social, Random)
  • Rest (R) = 15 s
  • 5 blocks per condition
  • Block sequence: [Soc, R, Soc, R, Rnd, R, Soc, R, Rnd, Soc, R, Rnd, R, Rnd, R, Soc, R, Rnd, R]
  • Dummy scans: first 25 time points (18 s)
  • Total scan time = 7 min

• 30_EVENT [2s_TR] [CNP_SST] [All_stop_trials]

  • Event-related design (UCLA Consortium for Neuropsychiatric Phenomics, Stop Signal Task)
  • TR = 2 s
  • Event duration = 1.5 s
  • Random interstimulus interval (ISI) = 0.5-4 s (mean ISI = 1 s)
  • 96 GO trials
  • 32 STOP-signal trials
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 7 min

• 31_EVENT [2s_TR] [CNP_SST] [Correct_stop_trials]

  • Unbalanced event-related design (UCLA Consortium for Neuropsychiatric Phenomics, Stop Signal Task)
  • TR = 2 s
  • Event duration = 1.5 s
  • Random interstimulus interval (ISI) = 0.5-4 s (mean ISI = 1 s)
  • 94 GO trials
  • 17 Correct STOP-signal trials
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 7 min

• 32_EVENT [2s_TR] [CNP_TST] [Switch_vs_NoSwitch]

  • Unbalanced event-related design (UCLA Consortium for Neuropsychiatric Phenomics, Task Switching Task)
  • TR = 2 s
  • Event duration = 1 s
  • Random interstimulus interval (ISI), mean ISI = 3 s
  • 24 Switch trials
  • 72 No Switch trials
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 6 min

• 33_BLOCK [2s_TR] [20s_DUR] [20_BLOCKS]

  • Block design
  • Repetition time (TR) = 2 s
  • Block duration = 20 s
  • 20 blocks per condition
  • Block sequence: [Cond_A, Rest, Cond_B, Rest, Cond_B, ... ]
  • Dummy scans: first 3 time points (6 s)
  • Total scan time = 26.6 min