filter_for_annotation in prune2df

[flde]

Thanks for the pySCENIC implementation! Can you please help me to understand what the filter_for_annotation in prune2df does? I checked the source code an there is no commend on the parameter. I can see that the default is True but for example in add_motif_url prune2df it is set to False. I am very thankful for clarification because setting filter_for_annotation=False returns TFs that I would expect to be active. However, i don't understand to what extent I might enrich for false positves too.

https://github.com/aertslab/pySCENIC/blob/d2309fed83759a0e66e0a995ef3d2f40bf4d6c1a/src/pyscenic/prune.py#L467C1-L476C6