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Description
How can we help
- Guidance and recommendations for methylation data types supported by cbioportal.
- How to format methylation data for import.
Describe the your question
Hi, I have methylation data I would like to import into a cbioportal instance.
The data I have is the output of the MEDIPS.meth() function. See here for details:
https://bioconductor.org/packages/release/bioc/manuals/MEDIPS/man/MEDIPS.pdf
The data has a row for every 250bp window of the genome, and columns containing: methylation counts, rpkm (Reads Per Kilobase per Million) and rms (root mean square) for each sample. It look something like this:
chr start stop CF sample1.counts sample2.counts sample1.rpkm sample2.rpkm sample1.rms sample2.rms
chr1 1 250 0 0 0 0 0 0 0
chr1 251 500 0 0 0 0 0 0 0
chr1 501 750 0 0 0 0 0 0 0
The existing methylation data format in cbioportal only supports one gene per row: (https://docs.cbioportal.org/file-formats/#methylation-data).
Is there any way to support this segmented methylation data format?
Perhaps using the Segmented Data format with a different 'genetic alteration type'? https://docs.cbioportal.org/file-formats/#segmented-data
I appreciate your help!