TCS provides different outputs depending on the number of CPUs

[apcamargo]

When I execute TCS I get different outputs depending on the number of CPUs being used. The difference between using 1 and 2 CPUs is quite large.

The results are consistent between runs using the same number of CPUs.

# t_coffee -infile out_enriched.fasta -evaluate -output score_ascii -n_core 1

T-COFFEE, Version_12.00.7fb08c2 (2018-12-11 09:27:12 - Revision 7fb08c2 - Build 211)
Cedric Notredame
CPU TIME:1 sec.
SCORE=60
*
 BAD AVG GOOD
*
All3007_000170_4_148_consensus      :  65
New_nucc_id_121273|21753_1_4_148    :  62
New_nucc_id_121789|22317_4_4_148    :  63
New_nucc_id_123461|24160_3_4_148    :  60
New_nucc_id_124155|24913_1_4_148    :  57
New_nucc_id_124546|25335_4_4_148    :  57
New_nucc_id_127104|28122_3_4_148    :  61
New_nucc_id_127252|28282_3_4_148    :  58

# t_coffee -infile out_enriched.fasta -evaluate -output score_ascii -n_core 2

T-COFFEE, Version_12.00.7fb08c2 (2018-12-11 09:27:12 - Revision 7fb08c2 - Build 211)
Cedric Notredame
CPU TIME:0 sec.
SCORE=601
*
 BAD AVG GOOD
*
All3007_000170_4_148_consensus      :  55
New_nucc_id_121273|21753_1_4_148    :  54
New_nucc_id_121789|22317_4_4_148    :  52
New_nucc_id_123461|24160_3_4_148    :  48
New_nucc_id_124155|24913_1_4_148    :  40
New_nucc_id_124546|25335_4_4_148    :  45
New_nucc_id_127104|28122_3_4_148    :  49
New_nucc_id_127252|28282_3_4_148    :  45

# t_coffee -infile out_enriched.fasta -evaluate -output score_ascii -n_core 8

T-COFFEE, Version_12.00.7fb08c2 (2018-12-11 09:27:12 - Revision 7fb08c2 - Build 211)
Cedric Notredame
CPU TIME:0 sec.
SCORE=601
*
 BAD AVG GOOD
*
All3007_000170_4_148_consensus      :  66
New_nucc_id_121273|21753_1_4_148    :  63
New_nucc_id_121789|22317_4_4_148    :  64
New_nucc_id_123461|24160_3_4_148    :  61
New_nucc_id_124155|24913_1_4_148    :  57
New_nucc_id_124546|25335_4_4_148    :  56
New_nucc_id_127104|28122_3_4_148    :  61
New_nucc_id_127252|28282_3_4_148    :  59

[cnotred]

Dear Antonio Thanks a lot for the report. Can you please PM me the sequences so I investigate further Cheers Cedric ################################### Dr Cedric Notredame Group Leader Notredame's lab - Comparative Bioinformatics Group Bioinformatics and Genomics Programme Room 440.03 Centre de Regulació Genòmica (CRG) Dr. Aiguader, 88 08003 Barcelona Spain Ph# + 34 93 316 02 71 Fax# + 34 93 316 00 99 Mobile# + 34 66 250 47 82 email ***@***.*** url www.tcoffee.org blog cedricnotredame.blogspot.com ORC-ID: 0000-0003-1461-0988 ###################################

…

On 2 Jun 2021, at 22:55, Antônio Pedro Camargo ***@***.***> wrote:  When I execute TCS I get different outputs depending on the number of CPUs being used. The difference between using 1 and 2 CPUs is quite large. The results are consistent between runs using the same number of CPUs. # t_coffee -infile out_enriched.fasta -evaluate -output score_ascii -n_core 1 T-COFFEE, Version_12.00.7fb08c2 (2018-12-11 09:27:12 - Revision 7fb08c2 - Build 211) Cedric Notredame CPU TIME:1 sec. SCORE=60 * BAD AVG GOOD * All3007_000170_4_148_consensus : 65 New_nucc_id_121273|21753_1_4_148 : 62 New_nucc_id_121789|22317_4_4_148 : 63 New_nucc_id_123461|24160_3_4_148 : 60 New_nucc_id_124155|24913_1_4_148 : 57 New_nucc_id_124546|25335_4_4_148 : 57 New_nucc_id_127104|28122_3_4_148 : 61 New_nucc_id_127252|28282_3_4_148 : 58 # t_coffee -infile out_enriched.fasta -evaluate -output score_ascii -n_core 2 T-COFFEE, Version_12.00.7fb08c2 (2018-12-11 09:27:12 - Revision 7fb08c2 - Build 211) Cedric Notredame CPU TIME:0 sec. SCORE=601 * BAD AVG GOOD * All3007_000170_4_148_consensus : 55 New_nucc_id_121273|21753_1_4_148 : 54 New_nucc_id_121789|22317_4_4_148 : 52 New_nucc_id_123461|24160_3_4_148 : 48 New_nucc_id_124155|24913_1_4_148 : 40 New_nucc_id_124546|25335_4_4_148 : 45 New_nucc_id_127104|28122_3_4_148 : 49 New_nucc_id_127252|28282_3_4_148 : 45 # t_coffee -infile out_enriched.fasta -evaluate -output score_ascii -n_core 8 T-COFFEE, Version_12.00.7fb08c2 (2018-12-11 09:27:12 - Revision 7fb08c2 - Build 211) Cedric Notredame CPU TIME:0 sec. SCORE=601 * BAD AVG GOOD * All3007_000170_4_148_consensus : 66 New_nucc_id_121273|21753_1_4_148 : 63 New_nucc_id_121789|22317_4_4_148 : 64 New_nucc_id_123461|24160_3_4_148 : 61 New_nucc_id_124155|24913_1_4_148 : 57 New_nucc_id_124546|25335_4_4_148 : 56 New_nucc_id_127104|28122_3_4_148 : 61 New_nucc_id_127252|28282_3_4_148 : 59 — You are receiving this because you are subscribed to this thread. Reply to this email directly, view it on GitHub, or unsubscribe.