Hybrid topologies for nucleic acids #6
Description
Hi, a project of mine involves single-stranded RNA/protein interactions, where we have some experimental / structural information on affinity changes based on single site mutations of the RNA sequence. I'm considering mutational free energy calculations as a complement to help prove our structural models.
I've noted in the code here that while there is no current support in mutate_v2.py to create hybrid topology files, there seems to be an intention of adding the relevant files (via adding mutres_dna.mtp, etc.)
Are there people who do intend to work on this that you know of? Or is this a paused feature?