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Dear,
I have a couple of mouse brain multiomics datasets comparing normal and trisomy samples. For ATAC seq analysis, we're having trouble identifying differential peaks and would like to make sure it's likely a real biology versus analysis issue. Will LSI integration be appropriate for integrating normal and trisomy datasets or should I consider additional normalization prior to integration?
Thank you
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Dear,
I have a couple of mouse brain multiomics datasets comparing normal and trisomy samples. For ATAC seq analysis, we're having trouble identifying differential peaks and would like to make sure it's likely a real biology versus analysis issue. Will LSI integration be appropriate for integrating normal and trisomy datasets or should I consider additional normalization prior to integration?
Thank you
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