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Pre-filter dbSNP loci to exclude targeted regions. #21

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alkaZeltser opened this issue Oct 24, 2023 · 0 comments
Open

Pre-filter dbSNP loci to exclude targeted regions. #21

alkaZeltser opened this issue Oct 24, 2023 · 0 comments
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@alkaZeltser
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          How about at least removing the targeted regions early which I assume are entirely redundant calculations?   I assume these intersection steps are fast compared to the coverage calculations.   I did also wonder why you don't want the regions neighboring the target regions?  Is there some technical problem with them?  I would have thought they would have interest, control regions or alternate splice regions for example.

Originally posted by @sorelfitzgibbon in #19 (comment)

@alkaZeltser alkaZeltser self-assigned this Oct 24, 2023
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