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_data/WP1531-datanodes.tsv

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@@ -14,7 +14,7 @@ CYP2R1 GeneProduct ncbigene:120227 "" ensembl:ENSG00000186104 ncbigene:120227 h
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DHCR7 GeneProduct ncbigene:1717 "" ensembl:ENSG00000172893 ncbigene:1717 hgnc.symbol:DHCR7 uniprot:A0A804HI25;uniprot:A0A804HL56;uniprot:E9PQ71;uniprot:E9PJ54;uniprot:B4E1K5;uniprot:H0YCS7;uniprot:H0YE57;uniprot:Q9UBM7;uniprot:E9PM00;uniprot:A0A024R5F7;uniprot:A0A8I5KRR9;uniprot:A0A804HJQ7;uniprot:E9PIP9;uniprot:H0YEJ5;uniprot:A0A804HJI8;uniprot:E9PRL8;uniprot:E9PLZ2
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CYP27A1 GeneProduct ncbigene:1593 "" ensembl:ENSG00000135929 ncbigene:1593 hgnc.symbol:CYP27A1 uniprot:Q02318;uniprot:F8WD90;uniprot:C9J1K5
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Vitamin D binding protein GeneProduct ncbigene:2638 "" ensembl:ENSG00000145321 ncbigene:2638 hgnc.symbol:GC uniprot:P02774;uniprot:D6RBJ7;uniprot:D6RF20;uniprot:D6RF35
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Alpha globulin GeneProduct :https://www.wikidata.org/wiki/Q2440935 ""
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Alpha globulin GeneProduct wikidata:Q2440935 ""
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RXRB GeneProduct ncbigene:6257 "" ensembl:ENSG00000204231 ncbigene:6257 hgnc.symbol:RXRB uniprot:Q5STP9;uniprot:P28702;uniprot:E9PK75;uniprot:A0A0S2Z570
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VDR GeneProduct ncbigene:7421 "" ensembl:ENSG00000111424 ncbigene:7421 hgnc.symbol:VDR uniprot:F8VVY8;uniprot:F8VRJ4;uniprot:F8VXQ9;uniprot:A0A5K1VW50;uniprot:F1D8P8;uniprot:F8VPF8;uniprot:P11473
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CYP24A1 GeneProduct ncbigene:1591 "" ensembl:ENSG00000019186 ncbigene:1591 hgnc.symbol:CYP24A1 uniprot:Q07973

_pathways/WP1531.md

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---
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annotations:
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- id: DOID:10609
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type: Disease Ontology
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value: rickets
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- id: CL:1000497
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parent: animal cell
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type: Cell Type Ontology
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value: kidney cell
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- id: CL:0002620
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parent: animal cell
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type: Cell Type Ontology
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value: skin fibroblast
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- id: PW:0000135
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: metabolic pathway of cofactors, vitamins, nutrients
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- id: PW:0001011
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: vitamin D metabolic pathway
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- id: DOID:10573
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type: Disease Ontology
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value: osteomalacia
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- id: CL:1000497
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parent: animal cell
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type: Cell Type Ontology
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value: kidney cell
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- id: CL:0000182
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parent: native cell
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type: Cell Type Ontology
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value: hepatocyte
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- id: DOID:10609
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type: Disease Ontology
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value: rickets
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- id: DOID:10573
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type: Disease Ontology
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value: osteomalacia
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- id: PW:0000135
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: metabolic pathway of cofactors, vitamins, nutrients
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authors:
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- Evelo
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- Lribeiro
@@ -75,15 +75,15 @@ description: Photochemical synthesis of vitamin D3 (cholecalciferol, D3) occurs
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growth, and immunity. VDR modulates the expression of genes by forming a heterodimer
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complex with retinoid-X-receptors (RXR). Proteins on this pathway have targeted
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assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP1531).
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last-edited: 2025-03-06
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last-edited: 2025-12-31
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ndex: ee30232e-8b62-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP1531
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- /instance/WP1531
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- /instance/WP1531_r137603
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revision: r137603
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- /instance/WP1531_r142298
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revision: r142298
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP1531.html

_pathways/WP1604.md

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parent: native cell
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type: Cell Type Ontology
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value: hepatocyte
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- id: DOID:2739
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parent: genetic disease
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type: Disease Ontology
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value: Gilbert syndrome
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- id: PW:0000107
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: xenobiotics biodegradation pathway
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- id: PW:0000754
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parent: drug pathway
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type: Pathway Ontology
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value: drug pathway
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- id: PW:0000107
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parent: classic metabolic pathway
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type: Pathway Ontology
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value: xenobiotics biodegradation pathway
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- id: DOID:2739
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parent: genetic disease
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type: Disease Ontology
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value: Gilbert syndrome
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authors:
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- Khanspers
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- AlexanderPico
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and morphine. A disease linked to this pathway is Gilbert syndrome (visualised
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in pink), which is characterized by impaired glucuronidation due to a polymorphism
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in the gene encoding UGT1A1.
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last-edited: 2025-11-04
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last-edited: 2025-12-31
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ndex: 508664cc-8b63-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP1604
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- /instance/WP1604
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- /instance/WP1604_r141113
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revision: r141113
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- /instance/WP1604_r142299
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revision: r142299
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP1604.html

_pathways/WP1946.md

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@@ -71,15 +71,15 @@ description: 'The Cori cycle is also known as the Lactic acid cycle, and refers
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the cycle cannot be sustained indefinitely. The Cori cycle shifts the metabolic
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burden from the muscles to the liver. Source: Adapted from [Wikipedia](https://en.wikipedia.org/wiki/Cori_cycle). Proteins
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on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP1946).'
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last-edited: 2025-12-31
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ndex: 67b302d9-8b63-11eb-9e72-0ac135e8bacf
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organisms:
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- Homo sapiens
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redirect_from:
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- /index.php/Pathway:WP1946
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- /instance/WP1946
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- /instance/WP1946_r139861
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revision: r139861
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- /instance/WP1946_r142301
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revision: r142301
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schema-jsonld:
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- '@context': https://schema.org/
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'@id': https://wikipathways.github.io/pathways/WP1946.html

assets/img/WP1531/WP1531-thumb.png

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assets/img/WP1604/WP1604-thumb.png

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assets/img/WP1946/WP1946-thumb.png

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