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Inconsistence between N_cells_per_location and the deconvolution result #381

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thestarocean opened this issue Sep 6, 2024 · 0 comments
Open

Inconsistence between N_cells_per_location and the deconvolution result #381

thestarocean opened this issue Sep 6, 2024 · 0 comments
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@thestarocean
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Thank you for providing such an amazing tool for spatial transcriptome analysis. However, when running it, I am somewhat confused by the inconsistence between N_cells_per_location and the deconvolution result.

I was running an analysis on sample collected from mouse liver. I gave the hyperparameter as N_cells_per_location equal to 10, but the deconvolution results showed that some spots had as many as ~20 hepatocytes.

WechatIMG379

Is this result normal? Or should I adjust the parameters somehow?
@thestarocean thestarocean added the question Further information is requested label Sep 6, 2024
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