Scripts and notebooks which generated results in the preprint:

Read our preprint here: Revising the ortholog conjecture in cross-species comparison of scRNA-seq data (v3)

Steps include:

• Gene classification using scRNA-seq data and the GeneSpectra module
• Plotting of gene classes (pie chart or bar chart) in one species
• Cross-species orthology mapping
• Cross-species ortholog gene class conservation analysis (gene class conservation heatmap)
• Cross-species cell type conservation of genes in different classes (pie charts)
• Comparing sequence similarity (bit score) and expression specificity similarity

Datasets include:

• Primate MTG data (5 species)
• Embryogenesis data (2 species)
• Cnidarian data (4 species)

Developer/maintainer: Yuyao Song, [email protected]