This repository contains all the codes used for analysing the IAM Frontier cohort data and for generating figures published in the cohort profile article.
- To compile all the codes, R 4.0 or later is recommended.
- For data preparation, R package "tidyverse" and "reshape2" are required.
- For generating plots, please install R package "gplots", "ggbiplot", "ComplexHeatmap", and "RColorBrewer" for the desired color schemes.
- To compute PCA of the genotype data, R package "flashpcaR" is used. The quality control is described in the genotype_qc_pca.sh file.
The data used for the analysis are not available in this repository. Due to participants' privacy, the data is available upon request to the I AM Frontier Project Data Access Committee for further research. We welcome collaboration with other research groups focused on personalized prevention, offering data sharing opportunities to advance research and improve healthcare outcomes.