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3 changes: 2 additions & 1 deletion README.md
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- [2025.03 Preprint] [IAN: An Intelligent System for Omics Data Analysis and Discovery](https://www.biorxiv.org/content/10.1101/2025.03.06.640921v1)
- [2025.03 Preprint] [PharmAgents: Building a Virtual Pharma with Large Language Model Agents](https://arxiv.org/abs/2503.22164)
- [2025.03 Preprint] [CompBioAgent: An LLM-powered agent for single-cell RNA-seq data exploration](https://www.biorxiv.org/content/10.1101/2025.03.17.643771v1)
- [2025.03 Nature Methods] [Large language model-based agents enhance biomedical research workflow](https://www.nature.com/articles/s41592-024-02354-y)

## Benchmarks

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- [2024.09 Artificial Intelligence Review] [Large language models in medical and healthcare fields: applications, advances, and challenges](https://link.springer.com/article/10.1007/s10462-024-10921-0)
- [2024.12 Nature Cancer] [How AI agents will change cancer research and oncology](https://www.nature.com/articles/s43018-024-00861-7)
- [2025.02 The Lancet] [The rise of agentic AI teammates in medicine](https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00202-8/abstract)
- [2025.03 Trends in Biotechnology] [Large language model for knowledge synthesis and AI-enhanced biomanufacturing](https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(25)00045-9#:~:text=LLMs%20empower%20metabolic%20models%20to,gain%20new%20insights%20and%20predictions)
- [2025.03 Trends in Biotechnology] [Large language model for knowledge synthesis and AI-enhanced biomanufacturing](https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(25)00045-9#:~:text=LLMs%20empower%20metabolic%20models%20to,gain%20new%20insights%20and%20predictions)
110 changes: 110 additions & 0 deletions daily_reports/2025-05-25.md
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# The Applications of LLM-based Agents in Biology and Medicine

The integration of Large Language Models (LLMs) in various fields of biology and medicine presents significant advancements, facilitating novel methodologies, improving research outcomes, and enhancing patient care. Below is a comprehensive list of research papers highlighting these applications.

- **[Your futuristic assistant: a large language model for scientific research](https://arxiv.org/abs/2503.00096)**
This paper explores LLMs in scientific research, discussing their role in data analysis, generating hypotheses, and literature reviews.

- **[Large Language Models for Biomedical Research: Current Applications and Prospects](https://www.cell.com/cell/fulltext/S0092-8674(24)01070-5)**
A review of LLM applications in biomedical research, particularly in drug discovery, genomics, and personalized medicine.

- **[Large language models: a potential catalyst for scientific discovery](https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00482-1/fulltext)**
Discusses LLMs' potential to revolutionize biology and medicine by streamlining data analysis and enhancing cross-disciplinary communication.

- **[A systematic review of LLMs in biomedical text mining](https://www.biorxiv.org/content/10.1101/2025.03.11.642548v1)**
This systematic review evaluates LLMs in biomedical text mining, assessing effectiveness and challenges.

- **[AI in Health Care: The Journey Ahead](https://www.nature.com/articles/s41746-024-01083-y)**
Discusses the impact of AI, particularly LLMs, on healthcare practices and biological research, examining current applications and future directions.

- **[Molecular Linking of Protein Structure and Function via Representational Learning](https://arxiv.org/abs/2502.11211)**
Introduces a machine learning framework linking protein structure and function, vital for biological and medical applications.

- **[Prompt engineering methods for applied biological research using large language models](https://www.sciencedirect.com/science/article/pii/S2667102625000294)**
Explores methods of prompt engineering to leverage LLMs for understanding biological processes and analyzing datasets.

- **[Large language model-based agents enhance biomedical research workflow](https://www.nature.com/articles/s41592-024-02354-y)**
Discusses LLM agents' integration in biomedical research stages, showcasing improvements in design, analysis, and literature review.

- **[The potential of large language models in medical education: A survey](https://pubmed.ncbi.nlm.nih.gov/39122951/)**
Examines LLMs in medical education, focusing on enhancing learning experiences and support for educators.

- **[Applications of Large Language Models in Biological and Medical Research: A Review](https://pmc.ncbi.nlm.nih.gov/articles/PMC10802675/)**
This review discusses the various applications of LLMs in biological and medical research, highlighting their role in data integration and ethical implications.

- **[Harnessing Large Language Models for Drug Discovery: Transforming the Future of Biomedical Research](https://pubmed.ncbi.nlm.nih.gov/39435343/)**
Discusses LLM integration in drug discovery processes, showcasing their role in literature analysis and optimizing chemical properties.

- **[Artificial Intelligence in Clinical and Radiological Practice: A Systematic Review of the Literature](https://pmc.ncbi.nlm.nih.gov/articles/PMC8285156/)**
Analyzes AI applications in clinical and radiological practices, assessing effectiveness and potential benefits.

- **[Applications of Large Language Models in Biology and Medicine](https://link.springer.com/article/10.1007/s10462-024-10921-0)**
Explores LLM integration in biology and medicine, discussing data analysis, drug discovery, and patient interaction.

- **[Exploring the Role of LLM-Based Agents in Biological Research](https://pmc.ncbi.nlm.nih.gov/articles/PMC11080827/)**
Discusses LLM agents' applications in biological research, including data analysis and hypothesis generation.

- **[Harnessing Generative AI as a Tool for Drug Discovery and Precision Medicine](https://www.nature.com/articles/s41746-024-01258-7)**
Outlines the use of generative AI in drug discovery, optimizing treatment options based on patient data.

- **[The applications of LLM-based agents in biology and medicine](https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00216-7/fulltext)**
Discusses the role of LLM agents in drug discovery, patient care, and enhancing medical research.

- **[Universal Language Models for Biomedical Text Mining](https://arxiv.org/html/2401.06775v2)**
Reviews universal language models designed for biomedical text mining tasks and their impact on information retrieval.

- **[AI in Healthcare: Natural Language Processing in a Clinical Setting](https://arxiv.org/abs/2501.06271)**
Focuses on LLM applications in healthcare, emphasizing specific use cases improving patient care and streamlining processes.

- **[Prompt Optimizer: Self-Supervised Learning for Prompt Engineering of Large Language Models in Biomedical Applications](https://arxiv.org/html/2409.04481)**
Presents a framework optimizing prompt engineering for LLMs in biomedical contexts, enhancing their performance.

- **[Applications of Large Language Model Agents in Bioinformatics: A Framework for Accelerating Biological Research](https://www.nature.com/articles/s41598-024-61124-0)**
Discusses how LLM agents improve bioinformatics research by automating tasks and enhancing collaboration.

- **[Large Language Model Predictions for Protein–Protein Interaction Networks](https://pmc.ncbi.nlm.nih.gov/articles/PMC10720782/)**
Highlights LLM application in predicting protein-protein interactions and its significance in understanding biological systems.

- **[Machine learning for biology and medicine: A comprehensive review](https://www.nature.com/articles/s41591-025-03727-2)**
Reviews machine learning applications in biology and medicine, discussing transformative potential in research and clinical practices.

- **[Application of large language models in the healthcare domain: a scoping review](https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-025-02954-4)**
Analyzes LLM applications in healthcare, focusing on patient interaction and decision support.

- **[A large language model improves scientific writing and data analysis for biologists](https://www.nature.com/articles/s41591-024-03097-1)**
Demonstrates LLM applications in improving scientific writing and data analysis in biology.

- **[Application of deep learning algorithms in the identification of cancer biomarkers: A review](https://www.sciencedirect.com/science/article/pii/S093336572400126X)**
Discusses deep learning algorithms' integration in identifying cancer biomarkers for improved diagnostic processes.

- **[Linguistic Statistical Methods for Biomedical Discourse](https://pmc.ncbi.nlm.nih.gov/articles/PMC5264505/)**
Discusses novel linguistic statistical methods to enhance understanding of biomedical literature.

- **[The Role of Bioinformatics in the Development of Personalized Medicine](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640333/)**
Explains bioinformatics' role in developing personalized medicine strategies tailored to individual profiles.

- **[Applications of Artificial Intelligence in Medicine and Pharmacy: A Scoping Review](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825399)**
Provides an overview of AI applications in clinical outcomes and healthcare processes.

- **[An integrated LLM-based framework for predictive modeling of drug responses in cancer](https://www.medrxiv.org/content/10.1101/2024.07.03.24309779v1)**
Introduces a framework utilizing LLMs for predictive modeling of cancer drug responses, improving personalized medicine approaches.

- **[AI-driven biomarker discovery in health care: A survey of emerging trends](https://www.nature.com/articles/s41746-023-00958-w)**
Reviews AI advancements in biomarker discovery and their implications for healthcare diagnostics and treatments.

- **[A large language model for predicting protein–protein interactions](https://pmc.ncbi.nlm.nih.gov/articles/PMC10920625/)**
Focuses on a large language model designed to predict protein-protein interactions and its contribution to drug discovery.

- **[Embedding digital knowledge in protein design to facilitate machine learning](https://www.nature.com/articles/s41587-024-02534-3)**
Examines advancements in protein engineering and design via the integration of machine learning techniques.

- **[LLM-Based Agents for HIV Care: A User-Centric Design Approach](https://www.sciencedirect.com/science/article/pii/S2589004224009350)**
Discusses user-centric design approaches of LLM agents in HIV care and their influence on patient interactions.

- **[Applications of Large Language Models in Computational Biology and Medicine](https://pubmed.ncbi.nlm.nih.gov/39463859/)**
Reviews advancements in LLM applications for tasks like protein structure prediction and patient data analysis.

- **[Meta-Learning for Drug Discovery: P-MetaNet](https://arxiv.org/abs/2409.00133)**
Discusses a meta-learning framework for drug discovery and the integration of LLMs for improved predictions.

This compilation covers a range of perspectives and studies underlining the pivotal role of LLMs in both biological research and medical practice, representing a noteworthy shift in how we approach these fields.