feat: add Dockerfile for building and installing openvariant

Dockerfile

@@ -0,0 +1,32 @@
+FROM ghcr.io/astral-sh/uv:0.5-python3.13-bookworm AS build-stage
+
+# Set environment variables
+ENV UV_COMPILE_BYTECODE=1
+
+# Set the working directory to /openvariant
+WORKDIR /openvariant
+
+# Stage necessary files into the container
+COPY uv.lock uv.lock
+COPY pyproject.toml pyproject.toml
+COPY openvariant openvariant
+COPY LICENSE LICENSE
+COPY README.md README.md
+
+# Install dependencies and build the project
+RUN mkdir -p /root/.cache/uv \
+    && uv sync --frozen --no-dev \
+    && uv build
+
+# Second stage: Runtime image
+FROM python:3.13-bookworm AS runtime-stage
+
+# Copy openvariant from the build stage
+COPY --from=build-stage /openvariant/dist /openvariant/dist
+WORKDIR /openvariant
+
+# Install openvariant
+RUN pip install dist/*.tar.gz 
+
+# Test the installation
+RUN openvar --help

README.md

@@ -64,6 +64,15 @@ pip install open-variant
 
 For more details check our [Installation](https://openvariant.readthedocs.io/en/latest/installation.html) section.
 
+### Running with Docker
+
+You can quickly build and run OpenVariant using [Dockerfile](./Dockerfile) without installing dependencies locally:
+
+```bash
+docker build -t openvariant .
+docker run --rm openvariant openvar --help
+```
+
 ## Examples
 
 We provide a variety of [examples](https://github.com/bbglab/openvariant/tree/master/examples) to help to understand how OpenVariant can be applied. Explore the