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#6 Cleaned up links and project.md contents. Added index to all page …
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josiahseaman committed Mar 25, 2020
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10 changes: 9 additions & 1 deletion README.md
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![](img/pantograph.png)
# graph-genome.github.io
Graph Genome Browser Documentation Website
[Go to Documentation Website](https://graph-genome.github.io/).
This is the source for the Pantograph Graph Genome Browser Documentation website.


## Documentation Index
* [Pantograph Description](https://graph-genome.github.io/pantograph.html)
* [Project Resources](https://graph-genome.github.io/project.html)
* [Our Team](https://docs.google.com/document/d/19SHq1P6aWBLKxJbMytW-qZEabWLtYVhoBU09C0uZlV8/edit?usp=sharing)
* [Hackathon](https://graph-genome.github.io/hackathon.html)
* [Get Involved](https://graph-genome.github.io/getinvolved.html)
8 changes: 8 additions & 0 deletions getinvolved.md
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Expand Up @@ -32,3 +32,11 @@ Anyone with these skills would be tremendously valuable to this project. Along t

The hackathon is a great way to get started with minimal commitment. Team leaders will help focus the development to ensure your success.


## Documentation Index
* [Complete Software Specification (gdoc)](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing)
* [Pantograph Description](pantograph.html)
* [Project Resources](project.html)
* [Our Team](https://docs.google.com/document/d/19SHq1P6aWBLKxJbMytW-qZEabWLtYVhoBU09C0uZlV8/edit?usp=sharing)
* [Hackathon](hackathon.html)
* [Get Involved](getinvolved.html)
8 changes: 8 additions & 0 deletions hackathon.md
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Expand Up @@ -53,3 +53,11 @@ There are a lot of tasks involved in managing a software development project.

The hackathon is a great way to get started with minimal commitment. Team leaders will help focus the development to ensure your success.


## Documentation Index
* [Complete Software Specification (gdoc)](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing)
* [Pantograph Description](pantograph.html)
* [Project Resources](project.html)
* [Our Team](https://docs.google.com/document/d/19SHq1P6aWBLKxJbMytW-qZEabWLtYVhoBU09C0uZlV8/edit?usp=sharing)
* [Hackathon](hackathon.html)
* [Get Involved](getinvolved.html)
19 changes: 9 additions & 10 deletions pantograph.md
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![](img/pantograph.png)

* [Github Docs](https://github.com/graph-genome/projects)
* [Complete Software Specification](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing)
* [Hackathon](https://github.com/virtual-biohackathons/covid-19-bh20/wiki/Pangenome-Browser)
* [Pantograph](pantograph.html)
* [Get Involved](getinvolved.html)


### COVID-19 Relevance

Pantograph as a project started in 2018 as a way to unlock the next level of population genetics for researchers. Pantograph is a visual browser for Graph Genomes, a new way of capturing sequence data. This process is designed to fix problems common to the sequencing technology that we’ve been using for the past 30 years. For example, Reference Bias means genetic analysis is more accurate for Europeans than for Africans ([Liverpool 2019](https://www.newscientist.com/article/2221957-genetic-studies-have-missed-important-gene-variants-in-african-people/)). A technical paper on Pantograph was being written by a team of 10 scientists before COVID-19 hit.
Expand All @@ -24,7 +17,7 @@ Our short-term goal is to extend the Pantograph tool to add features to make it
Scientists frequently use Multiple Sequence Alignment (MSA) to compare many genomes simultaneously and highlight their differences. MSA works by inserting gaps in all individuals to allow space for unique sequence in one or more individuals. This technique can lead to **Reference Bias** in analyzing diverse sequences. Graph Genomes are a new way of storing an alignment between many sequences that can include **non-linear rearrangements**. For example, the middle of one sequence can be at the beginning of another sequence. Tools for Graph Genomes are still under development and can't reliably scale to thousands of individuals. Pantograph is the first graph genome browser design with the capability to **scale to thousands of individuals** and still show the individual's nucleotide sequence. This means it's uniquely suited to providing a global overview of species genetic diversity with the option to zoom in on small features.

The complete details of Pantograph and its planned capabilities are available in the
[Pantograph Specification](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing). The key aspects of our approach are:
**[Pantograph Specification](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing)**. The key aspects of our approach are:
1) Use Graph Sorting to find a consensus ordering of elements in the genome
2) Separate genome into colinear blocks called Components
3) Show SNPs and indels as cells within a Component grid (Matrix)
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If you're not available right away, but would like to join the team, the Hackathon is a great opportunity. We will be hosting a special event for volunteers to collaborate for one week. We hope to build the software to a point where we can analyze the variations of the SARS-CoV-2 virus by the end of April. Your contribution could be important to helping us stop this killer virus.

Join us to extend Pantograph so that it can be used to help with the COVID-19 outbreak.

[View Details](hackathon.md)
[Hackathon Details](hackathon.md)


## Documentation Index
* [Complete Software Specification (gdoc)](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing)
* [Pantograph Description](pantograph.html)
* [Project Resources](project.html)
* [Our Team](https://docs.google.com/document/d/19SHq1P6aWBLKxJbMytW-qZEabWLtYVhoBU09C0uZlV8/edit?usp=sharing)
* [Hackathon](hackathon.html)
* [Get Involved](getinvolved.html)
38 changes: 16 additions & 22 deletions project.md
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![](img/pantograph.png)

# Pantograph Pangenome Browser

This page is a work in progress. GitHub Issues will be created for each planned Feature or bug found by testers.

## Github

* [Graph Genome Browser Consortium](https://github.com/graph-genome)
* [Github Docs](https://github.com/graph-genome/graph-genome.github.io)
# Proejct Details and Resources

This page is for the software details and logistics of working on the project. It's a work in progress. GitHub Issues will be created for each planned Feature or bug found by testers.

## Project Documents

* [Project Details](https://github.com/orgs/graph-genome/projects)
* [Schematize Project Board](https://github.com/orgs/graph-genome/projects/3)
* [JBrowse Annotation Integration Project Board](https://github.com/orgs/graph-genome/projects/2)
* [Data standards in pipeline Project Board](https://github.com/orgs/graph-genome/projects/1)
* [Graph Genome Browser Specification](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74)
* [Github Docs](https://github.com/graph-genome/graph-genome.github.io)



## Web Pages

* [About the Project](project.html)
* Top-Level [Graph Genome Browser Consortium GitHub](https://github.com/graph-genome)
* [Project Details](https://github.com/orgs/graph-genome/projects)
* [Schematize Project Board](https://github.com/orgs/graph-genome/projects/3)
* [JBrowse Annotation Integration Project Board](https://github.com/orgs/graph-genome/projects/2)
* [Data standards in pipeline Project Board](https://github.com/orgs/graph-genome/projects/1)
* [Graph Genome Browser Specification (gdoc)](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74)
* [Source for these Docs](https://github.com/graph-genome/graph-genome.github.io)


## Documentation Index
* [Complete Software Specification (gdoc)](https://docs.google.com/document/d/1NEYkRS6Ux1w_v0Soe74FeOAMOxGHOzDun00LdjMi-74/edit?usp=sharing)
* [Pantograph Description](pantograph.html)
* [Project Resources](project.html)
* [Our Team](https://docs.google.com/document/d/19SHq1P6aWBLKxJbMytW-qZEabWLtYVhoBU09C0uZlV8/edit?usp=sharing)
* [Hackathon](hackathon.html)
* [Pantograph Documents](pantograph.html)
* [Get Involved](getinvolved.html)


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