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Model of neuronal chloride homeostasis, including impermeant anions and KCC2 transporters, for the 2018 eLife paper "Biophysical model reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis"

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Model of neuronal chloride homeostasis

Single compartment model (this repo)

Figures 1 through 6 of the paper "Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis" by Düsterwald, Currin, Burman, Akerman, Kay and Raimondo

If you would like a demonstration of the first section of figures in the paper (https://www.biorxiv.org/content/early/2017/11/08/216150), see the notebook "runme_figures_1_to_6" in this repo.

Multi-compartment model (multi-compartment-model submodule)

Figures 7 and 8 of the paper "Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis" by Düsterwald, Currin, Burman, Akerman, Kay and Raimondo

If you would like a demonstration of the latter section of figures in the paper and demonstrations of neuronal chloride homeostatic mechanisms across multiple compartments (incorporating electrodiffusion), see the notebook "runme_figures_7_and_8" in the submodule "multi-compartment-model" (https://github.com/Chris-Currin/multi-compartment_multi-anion), which can be navigated to directly from this repo.

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Model of neuronal chloride homeostasis, including impermeant anions and KCC2 transporters, for the 2018 eLife paper "Biophysical model reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis"

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