Minimap2-2.1 (r311)
This release adds spliced alignment for long noisy RNA-seq reads. On a SMRT
Iso-Seq and a Oxford Nanopore data sets, minimap2 appears to outperform
traditional mRNA aligners. For DNA alignment, this release gives almost
identical output to v2.0. Other changes include:
-
Added option
-R
to set the read group header line in SAM. -
Optionally output the
cs:Z
tag in PAF to encode both the query and the
reference sequences in the alignment. -
Fixed an issue where DP alignment uses excessive memory.
The minimap2 technical report has been updated with more details and the
evaluation of spliced alignment:
- Li, H. (2017). Minimap2: fast pairwise alignment for long nucleotide
sequences. arXiv:1708.01492v2.
(2.1: 25 August 2017, r311)