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Minimap2-2.1 (r311)

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@lh3 lh3 released this 25 Aug 05:37
· 905 commits to master since this release

This release adds spliced alignment for long noisy RNA-seq reads. On a SMRT
Iso-Seq and a Oxford Nanopore data sets, minimap2 appears to outperform
traditional mRNA aligners. For DNA alignment, this release gives almost
identical output to v2.0. Other changes include:

  • Added option -R to set the read group header line in SAM.

  • Optionally output the cs:Z tag in PAF to encode both the query and the
    reference sequences in the alignment.

  • Fixed an issue where DP alignment uses excessive memory.

The minimap2 technical report has been updated with more details and the
evaluation of spliced alignment:

  • Li, H. (2017). Minimap2: fast pairwise alignment for long nucleotide
    sequences. arXiv:1708.01492v2.

(2.1: 25 August 2017, r311)