Releases: lh3/minimap2
Minimap2-2.1 (r311)
This release adds spliced alignment for long noisy RNA-seq reads. On a SMRT
Iso-Seq and a Oxford Nanopore data sets, minimap2 appears to outperform
traditional mRNA aligners. For DNA alignment, this release gives almost
identical output to v2.0. Other changes include:
-
Added option
-Rto set the read group header line in SAM. -
Optionally output the
cs:Ztag in PAF to encode both the query and the
reference sequences in the alignment. -
Fixed an issue where DP alignment uses excessive memory.
The minimap2 technical report has been updated with more details and the
evaluation of spliced alignment:
- Li, H. (2017). Minimap2: fast pairwise alignment for long nucleotide
sequences. arXiv:1708.01492v2.
(2.1: 25 August 2017, r311)
Minimap2-2.0 (r275)
This release is identical to version 2.0rc1, except the version number. It is
described and evaluated in the following technical report:
- Li, H. (2017). Minimap2: fast pairwise alignment for long DNA sequences.
arXiv:1708.01492v1.
(2.0: 8 August 2017, r275)
Minimap2-2.0rc1 (r232)
This release improves the accuracy of long-read alignment and added several
minor features.
-
Improved mapping quality estimate for short alignments containing few seed
hits. -
Fixed a minor bug that affects the chaining accuracy towards the ends of a
chain. Changed the gap cost for chaining to reduce false seeding. -
Skip potentially wrong seeding and apply dynamic programming more frequently.
This slightly increases run time, but greatly reduces false long gaps. -
Perform local alignment at Z-drop break point to recover potential inversion
alignment. Output the SA tag in the SAM format. Added scripts to evaluate
mapping accuracy for reads simulated with pbsim.
This release completes features intended for v2.0. No major features will be
added to the master branch before the final v2.0.
(2.0rc1: 30 July 2017, r232)