Other Organisms

Using Mutalyzer with sequences from other organisms

The following Mutalyzer tools work for all organisms:

• Name Checker,
• Syntax Checker,
• Name Generator,
• Description Extractor,
• Reference File Loader,
• and the batch checker versions of these tools.

Mutalyzer can process GenBank reference sequence records from other organisms than man and will apply the appropriate coding table to translate an open reading frame into a protein sequence. Please note that all variants will be described according to the HGVS standard human sequence variation nomenclature. When trying to retrieve genomic reference sequences using gene symbols with the Reference File Loader or when specifying a particular gene in a genomic reference sequence, the gene symbol should be similar to that used in the (genome) sequence annotation.

Name Checker Example: NM_001002489.2:c.259G>T, which would describe a Zebrafish (D. rerio) sdhda variant equivalent to the human SDHD variant example, provides the following results.