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mvinyard/README.md

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I'm currently working on my PhD at Harvard University where I am developing methods for the analysis of single-cell genomics data. I also work on methods for CRISPR-Cas9-based genome-editing tools (like base-editing) to study cancer progression. My PhD work is funded by an NIH F31 award through the NCI and focuses on applying innovations in deep learning to analogous problems in the analysis of single-cell data. You can read more about me and my studies at my website.

I am passionate about and interested in:

  • 🧿 (single-cell) epigenomics and chromatin biology
  • 🧬 Functional annotation of variation in the human genome
  • 🧮 Deep learning
  • ✂️ Functional CRISPR studies
  • 🧠 Psychiatric disorders
  • 🧫 Cancer biology
  • 🐍 Implementing open-source tools for genomics in python.
  • 🎨 Computer graphics art

Links

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Repos and software libraries


Deep learning

torch-adata-logoneural-diffeqs-logotorch-composerannoyance-logo

Bioinformatics: CRISPR and other assays (single-cell and bulk)

cell-tools-logoseq-toolkit-logosglib-logoann_nmf-logo

Python developer utility packages and plotting

pysdk-logovinplots-logolicorice-logo



For tutorials and resources: link

GitHub Stats


Selected Publications and preprints


  • Michael E. Vinyard, et al. . Nat. Chem. Biol. DOI: 10.1038/s41589-019-0263-0 (2019).
  • Chen, H., Lareau, C.†, Andreani, T.†, Michal E. Vinyard†, et al. . Genome Biol. DOI: 10.1186/s13059-019-1854-5 (2020).
  • GitHub
  • Huidong Chen, Jayoung Ryu, Michael E. Vinyard, Adam Lerer, & Luca Pinello. . bioRxiv, DOI: 2021.2010.2017.464750 (2021).
  • GitHub
  • docs
  • L. Wang†, Q. Zhang†, Q. Qin†, N. Trasanidis†, Michael E. Vinyard†, et al., . Curr. Opin. in Syst. Biol. ISSN 2452-3100. DOI: 10.1016/j.coisb.2021.03.006 (2021).
  • Stein, D.†, Chen, H.†, Vinyard, M.E.†, et al. . Front. genet. DOI: 10.1101/2020.07.30.229534 (2021).
  • GitHub
  • singlecellVR.com

made-with-Markdown GitHub forks GitHub stars

Dyanmically generated stats are implemented from GitHub Readme Stats

† denotes equal contribution

Pinned Loading

  1. annoyance annoyance Public

    AnnData-compatible wrapper of Spotify's annoy library.

    Python 1

  2. lightning-tutorial lightning-tutorial Public

    PyTorch-Lightning Tutorial

    Jupyter Notebook 9

  3. ArchR-h5ad ArchR-h5ad Public

    Parse ArchR arrow files to anndata h5ad

    Python 14 3

  4. torch-adata torch-adata Public

    Create PyTorch Datasets from AnnData

    Jupyter Notebook 20

  5. torch-nets torch-nets Public

    Compose PyTorch Neural Networks

    Python

  6. AnnDataQuery AnnDataQuery Public

    Fetch and format data matrices from AnnData

    Jupyter Notebook