Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Adding --maxVariantFrac and --minOppositeDepth to MethylDackel (Bwameth option) #404

Open
LucaZanella15 opened this issue Jun 18, 2024 · 1 comment
Labels
enhancement New feature or request

Comments

@LucaZanella15
Copy link

LucaZanella15 commented Jun 18, 2024

Description of feature

Hi all,

I think that adding the possibility to provide the --maxVariantFrac option (and its --minOppositeDepth counterpart, by default set to 0) would be of great value.

The possibility to switch on and off --keepDupes (currently by default properly being on) would also be useful to account for current EM-seq library preparation technologies that produce complex libraries that have low probability of fragments having the same start and stop positions unless they are true duplicates

@LucaZanella15 LucaZanella15 added the enhancement New feature or request label Jun 18, 2024
@sateeshperi
Copy link
Contributor

hi @LucaZanella15 couldn't these set in ext.args of methydackel ? could you explain more on why it would be good to add by default ?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
enhancement New feature or request
Projects
None yet
Development

No branches or pull requests

2 participants