dsb v2.0.0 is now on CRAN: https://cran.r-project.org/package=dsb
This update increases speed 10-fold with the fast.km argument. See vignettes. This can be used with ModelNegativeADTnorm to normalize large datasets without empty droplets, or with the original version of the function requiring empty drops, DSBNormalizeProtein. This version also has various improvements to documentation and some streamlining of internal code.
news.md file: https://github.com/niaid/dsb/blob/master/NEWS.md