Coot is a toolkit for Macromolecular Crystallography and model-building. Coot uses GTK widgets mmdb, clipper, and OpenGL to provide interactive tools for model-building, refinement and validation.
The easiest way to install Coot is using package managers.
After installing Homebrew run the commands below.
brew install brewsci/bio/coot
coot
After installing Flatpak and registering Flathub run the commands below.
(You will need admin privileges to install Flatpak with sudo
.)
flatpak install flathub io.github.pemsley.coot
# Simply click Coot's icon in the menu or
flatpak run io.github.pemsley.coot
See this.