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popsim-consortium · Aug 19, 2023 · 1e2d12a · 1e2d12a
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diff --git a/main/_images/sec_catalog_anapla_models_mallardblackduck_2l19.png b/main/_images/sec_catalog_anapla_models_mallardblackduck_2l19.png
diff --git a/main/_images/sec_catalog_homsap_models_americanadmixture_4b11.png b/main/_images/sec_catalog_homsap_models_americanadmixture_4b11.png
diff --git a/main/_images/sec_catalog_homsap_models_outofafrica_2t12.png b/main/_images/sec_catalog_homsap_models_outofafrica_2t12.png
diff --git a/main/_images/sec_catalog_homsap_models_outofafrica_3g09.png b/main/_images/sec_catalog_homsap_models_outofafrica_3g09.png
diff --git a/main/_images/sec_catalog_homsap_models_outofafrica_4j17.png b/main/_images/sec_catalog_homsap_models_outofafrica_4j17.png
diff --git a/main/_images/sec_catalog_homsap_models_outofafricaarchaicadmixture_5r19.png b/main/_images/sec_catalog_homsap_models_outofafricaarchaicadmixture_5r19.png
diff --git a/.../sec_catalog_homsap_models_outofafricaextendedneandertaladmixturepulse_3i21.png b/.../sec_catalog_homsap_models_outofafricaextendedneandertaladmixturepulse_3i21.png
diff --git a/main/_images/sec_catalog_homsap_models_papuansoutofafrica_10j19.png b/main/_images/sec_catalog_homsap_models_papuansoutofafrica_10j19.png
diff --git a/main/_images/sec_catalog_pantro_models_bonoboghost_4k19.png b/main/_images/sec_catalog_pantro_models_bonoboghost_4k19.png
diff --git a/main/_images/sec_catalog_ponabe_models_twospecies_2l11.png b/main/_images/sec_catalog_ponabe_models_twospecies_2l11.png
diff --git a/main/catalog.html b/main/catalog.html
@@ -230,6 +230,7 @@
 <li class="toctree-l4"><a class="reference internal" href="#sec_catalog_homsap_dfes_gamma_k17">Gamma_K17</a></li>
 <li class="toctree-l4"><a class="reference internal" href="#sec_catalog_homsap_dfes_gamma_h17">Gamma_H17</a></li>
 <li class="toctree-l4"><a class="reference internal" href="#sec_catalog_homsap_dfes_lognormal_h17">LogNormal_H17</a></li>
+<li class="toctree-l4"><a class="reference internal" href="#sec_catalog_homsap_dfes_mixed_k23">Mixed_K23</a></li>
 </ul>
 </li>
 </ul>
@@ -6500,6 +6501,10 @@ <h3>Distribution of Fitness Effects (DFEs)<a class="headerlink" href="#sec_catal
 <td><p>2017</p></td>
 <td><p>Deleterious Log-normal DFE</p></td>
 </tr>
+<tr class="row-odd"><td><p><a class="reference internal" href="#sec_catalog_homsap_dfes_mixed_k23">Mixed_K23</a></p></td>
+<td><p>2023</p></td>
+<td><p>Deleterious Gamma DFE with additional lethals</p></td>
+</tr>
 </tbody>
 </table>
 <section id="sec_catalog_homsap_dfes_gamma_k17">
@@ -6526,6 +6531,14 @@ <h3>Distribution of Fitness Effects (DFEs)<a class="headerlink" href="#sec_catal
 <li><p>Huber et al., 2017. <a class="reference external" href="https://doi.org/10.1073/pnas.1619508114">https://doi.org/10.1073/pnas.1619508114</a></p></li>
 </ul>
 </section>
+<section id="sec_catalog_homsap_dfes_mixed_k23">
+<span id="sec_catalog_homsap_dfes_mixed_k23"></span><h4>Mixed_K23<a class="headerlink" href="#sec_catalog_homsap_dfes_mixed_k23" title="Permalink to this heading"></a></h4>
+<p>Deleterious Gamma DFE with additional lethals</p>
+<p class="rubric">Citations</p>
+<ul class="simple">
+<li><p>Kyriazis et al., 2023. <a class="reference external" href="https://doi.org/10.1086/726736">https://doi.org/10.1086/726736</a></p></li>
+</ul>
+</section>
 </section>
 </section>
 <hr class="docutils" />

diff --git a/main/cli_arguments.html b/main/cli_arguments.html
@@ -1865,8 +1865,8 @@ <h4>Named Arguments<a class="headerlink" href="#named-arguments_repeat17" title=
 <p>Specify a simulation model. If no model is specified, a single population constant size model is used. Available models: OutOfAfricaExtendedNeandertalAdmixturePulse_3I21, OutOfAfrica_3G09, OutOfAfrica_2T12, Africa_1T12, AmericanAdmixture_4B11, OutOfAfricaArchaicAdmixture_5R19, Zigzag_1S14, AncientEurasia_9K19, PapuansOutOfAfrica_10J19, AshkSub_7G19, OutOfAfrica_4J17, Africa_1B08, AncientEurope_4A21. Please see –help-models for details of these models.</p>
 </dd>
 <dt><kbd>--dfe</kbd></dt>
-<dd><p>Possible choices: Gamma_K17, Gamma_H17, LogNormal_H17</p>
-<p>Specify a Distribution of Fitness Effects (DFE) model. If no DFE is specified, all mutations are neutral. Available DFE models:Gamma_K17, Gamma_H17, LogNormal_H17. Please see –help-dfes for details of these DFE models.</p>
+<dd><p>Possible choices: Gamma_K17, Gamma_H17, LogNormal_H17, Mixed_K23</p>
+<p>Specify a Distribution of Fitness Effects (DFE) model. If no DFE is specified, all mutations are neutral. Available DFE models:Gamma_K17, Gamma_H17, LogNormal_H17, Mixed_K23. Please see –help-dfes for details of these DFE models.</p>
 </dd>
 <dt><kbd>--dfe-interval</kbd></dt>
 <dd><p>Specify the interval where selection (given a DFE) is simulated. Anything outside of the interval is simulated as neutral. If no interval is specified, selection is simulated across the entire contig. The interval is written as ‘start,end’ (separated by a comma, with no space, for instance: –dfe-interval 1000,2000.</p>

diff --git a/main/objects.inv b/main/objects.inv
diff --git a/main/searchindex.js b/main/searchindex.js