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pavlovicmilena committed Apr 11, 2024
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10 changes: 10 additions & 0 deletions README.md
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Expand Up @@ -102,3 +102,13 @@ ligo specs.yaml output_folder
```

Note that `output_folder` (user-defined name) should not exist before the run.


## Citing LIgO

If you are using LIgO in any published work, please cite:

Chernigovskaya, M.; Pavlović, M.; Kanduri, C.; Gielis, S.; Robert, P. A.; Scheffer, L.; Slabodkin, A.; Haff, I. H.; Meysman, P.; Yaari, G.; Sandve, G. K.; Greiff, V
“Simulation of Adaptive Immune Receptors and Repertoires with Complex Immune Information to Guide the Development and Benchmarking of AIRR Machine Learning”
bioRxiv, 2023, 2023.10.20.562936. https://doi.org/10.1101/2023.10.20.562936.

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14 changes: 6 additions & 8 deletions docs_source/index.rst
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Expand Up @@ -3,6 +3,8 @@ Welcome to the LIgO documentation!

LIgO is a Python tool for simulation of adaptive immune receptors (AIRs) and repertoires (AIRRs) with known ground-truth immune signals for the development and benchmarking of AIRR-based machine learning. To get started using LigO right now, check out our :doc:`quickstart` tutorial.

.. image:: ./_static/figures/ligo_pipeline.png

Why should you use LIgO?
---------------------------------
* LIgO makes **simulations reproducible**, all simulation parameters are specified through a YAML file.
Expand All @@ -12,22 +14,18 @@ Why should you use LIgO?
* LIgO **guides the user** and helps to set optimal simulation parameters.
* LIgO outputs detailed information about presence and position(s) of immune signal(s) for every AIR in AIRR-compliant format.

**Please check out LIgO manuscript (link will be added soon) for more information!**
Please **check out LIgO manuscript** `(biorxiv link) <https://www.biorxiv.org/content/10.1101/2023.10.20.562936v2>`_ for more information!

Contents
---------------------------------

.. toctree::
:maxdepth: 1
:caption: Contents

quickstart
installation
tutorials
usecases
specification


Indices and tables
==================

* :ref:`genindex`
* :ref:`modindex`
* :ref:`search`
4 changes: 2 additions & 2 deletions docs_source/installation.rst
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Expand Up @@ -42,13 +42,13 @@ Alternatively, to install LIgO from GitHub run the following:
pip install git+https://github.com/uio-bmi/ligo.git
4. To be able to export full-length sequences, it is necessary to also download the reference data using Stitchr:
4. To be able to export full-length TCR sequences, it is necessary to also download the reference data using Stitchr:

.. code-block:: console
stitchrdl -s human
For more information on downloading data using Stitchr, see `Stitcher documentation <https://jamieheather.github.io/stitchr/installation.html>`_.
For more information on downloading data using Stitchr, see `Stitcher documentation <https://jamieheather.github.io/stitchr/installation.html>`_. Once the Stitchr reference data has been downloaded, LigO will automatically include full-length TCR sequences in the output.


Use LIgO with Docker
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