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| 1 | +ID Database Citation |
| 2 | +23477830 Pubmed "Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF. Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, et al. Cancer Cell. 2013 Mar 18;23(3):302–15. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/23477830"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/23477830"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/23477830"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 3 | +25218591 Pubmed "2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy. Zhang D, Li J, Wang F, Hu J, Wang S, Sun Y. Cancer Lett. 2014 Dec 28;355(2):176–83. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/25218591"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/25218591"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/25218591"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 4 | +25297634 Pubmed "Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma. Gopal YNV, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, et al. Cancer Res. 2014 Dec 1;74(23):7037–47. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/25297634"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/25297634"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/25297634"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 5 | +26139106 Pubmed "Vemurafenib resistance reprograms melanoma cells towards glutamine dependence. Hernandez-Davies JE, Tran TQ, Reid MA, Rosales KR, Lowman XH, Pan M, et al. J Transl Med. 2015 Jul 3;13:210. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/26139106"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/26139106"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/26139106"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 6 | +26699902 Pubmed "Enhanced OXPHOS, glutaminolysis and β-oxidation constitute the metastatic phenotype of melanoma cells. Rodrigues MF, Obre E, de Melo FHM, Santos GC Jr, Galina A, Jasiulionis MG, et al. Biochem J. 2016 Mar 15;473(6):703–15. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/26699902"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/26699902"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/26699902"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 7 | +27043285 Pubmed "Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors. Zhang G, Frederick DT, Wu L, Wei Z, Krepler C, Srinivasan S, et al. J Clin Invest. 2016 May 2;126(5):1834–56. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/27043285"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/27043285"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/27043285"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 8 | +29309612 Pubmed "Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma. Audrito V, Managò A, La Vecchia S, Zamporlini F, Vitale N, Baroni G, et al. J Natl Cancer Inst. 2018 Mar 1;110(3):10.1093/jnci/djx198. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/29309612"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/29309612"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/29309612"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 9 | +29440170 Pubmed "RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma. Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, et al. Cancer Res. 2018 May 1;78(9):2191–204. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/29440170"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/29440170"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/29440170"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 10 | +30086340 Pubmed "Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells. Li X, Wu J, Zhang X, Chen W. Free Radic Biol Med. 2018 Dec;129:256–67. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/30086340"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/30086340"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/30086340"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 11 | +31375515 Pubmed "A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors. Aloia A, Müllhaupt D, Chabbert CD, Eberhart T, Flückiger-Mangual S, Vukolic A, et al. Clin Cancer Res. 2019 Nov 15;25(22):6852–67. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/31375515"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/31375515"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/31375515"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 12 | +32620791 Pubmed "Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth. Ishak Gabra MB, Yang Y, Li H, Senapati P, Hanse EA, Lowman XH, et al. Nat Commun. 2020 Jul 3;11(1):3326. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/32620791"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/32620791"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/32620791"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 13 | +34862480 Pubmed "Targeting cancer metabolism in the era of precision oncology. Stine ZE, Schug ZT, Salvino JM, Dang CV. Nat Rev Drug Discov. 2022 Feb;21(2):141–62. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/34862480"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/34862480"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/34862480"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 14 | +35231572 Pubmed "Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming. Chang MT, Tsai LC, Nakagawa-Goto K, Lee KH, Shyur LF. Pharmacol Res. 2022 Apr;178:106148. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/35231572"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/35231572"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/35231572"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 15 | +37419033 Pubmed "Fatty acid oxidation supports melanoma cell migration through autophagy regulation. Shin S, Yang S, Kim M, Lee EK, Hur SC, Jeong SM. Biochem Biophys Res Commun. 2023 Sep 24;674:124–32. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/37419033"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/37419033"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/37419033"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 16 | +37758066 Pubmed "PGC1-α-driven mitochondrial biogenesis contributes to a cancer stem cell phenotype in melanoma. Fontana F, Macchi C, Anselmi M, Rizzuto AS, Ruscica M, Limonta P. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166897. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/37758066"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/37758066"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/37758066"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 17 | +38862714 Pubmed "Nutrient-delivery and metabolism reactivation therapy for melanoma. Chen Y, Wang C, Wu Y, Wang Y, Meng Y, Wu F, et al. Nat Nanotechnol. 2024 Sep;19(9):1399–408. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/38862714"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/38862714"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/38862714"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 18 | +39536973 Pubmed "Cellulose nanocrystal-annealed hydrogel system for local chemo-metabolic therapy of melanoma. Jeong DI, Hao Q, Lee SY, Kim S, Karmakar M, Chu S, et al. J Control Release. 2025 Jan 10;377:324–38. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/39536973"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/39536973"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/39536973"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 19 | +39579354 Pubmed "ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis. Hlavaty SI, Salcido KN, Pniewski KA, Mukha D, Ma W, Kannan T, et al. Cell Rep. 2024 Dec 24;43(12):114988. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/39579354"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/39579354"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/39579354"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
| 20 | +40617808 Pubmed "Metabolic reprogramming in melanoma therapy. Shen D, Zhang L, Li S, Tang L. Cell Death Discov. 2025 Jul 5;11(1):308. <a href=""http://www.ncbi.nlm.nih.gov/pubmed/40617808"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/40617808"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/40617808"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>" |
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