[0.9.1] (21 Jan 2025)
This release of Dorado brings significant basecalling speed improvements for Nvidia GPUs with compute capabilities 8.6 (Ampere – e.g., RTX A6000), 8.7 (Ampere – e.g., Orin family), and 8.9 (Ada Lovelace). Additionally, dorado polish
receives major enhancements, including the introduction of the --bacteria
flag, which optimizes basecalling for native bacterial and methylated DNA. The updated dorado polish
is now compatible with data basecalled using v4.3 and v4.2 models and serves as a beta-stage replacement for Medaka.
- d46286e - Upgraded to Koi v0.5.3 for optimised basecalling on CC 8.6, 8.7 & 8.9
- 9c83c49 - Added VCF output to the Dorado
polish
- d859977 - Improve messaging when an unrecognised model complex is specified
- 06f6239 - Support for legacy count models in Dorado
polish
- e51d64f - Fixed precision issue with Dorado
polish
qscore normalisation - d50494d - Added
--bacteria
support for Doradopolish
- f3fa447 - Added ULK114 kits to adapter/primer trimming LUT
- 1a4316e - Dorado
polish
algorithm improvements and refactoring - a0fc960 - Dorado
polish
option-o
now writes to a directory - 7ae31a8 - Dorado
polish
fix for parsing FASTA file inputs - b382344 - Dorado
polish
models are now included in Doradodownload
--list
,--list-yaml
, and--list-structured
- adebcc5 - Ensure Q-score and read length filters are applied to reads after trimming
- 96d574d - Enforce use of
--kit-name
for Doradodemux
custom barcodes to prevent unclassified reads - 62c86d0 - Support
CUDA_VISIBLE_DEVICES
for UUIDs or integers - c39f906 - Prevent crashing in auto batchsize due to short chunksizes