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v0.2.3

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@modkit-bot modkit-bot released this 02 Dec 02:32
· 214 commits to master since this release

Adds

  • [dmr, multi] Allow site-level scoring by omitting the --regions argument. Sites will be collected from the input bedMethyl files.
  • [dmr] Friendlier handling of missing files and when regions aren't found in the bedMethyl input files.
  • [dmr] allow filtering on valid coverage without changing input
  • [extract] output "read calls" extract table, a TSV with the base modification calls for every modified position in every read using the same thresholding algorithm as pileup
  • [extract] allow filtering of calls by reference motif (like in pileup) as well as BED regions (and exclude regions)

Fixes

  • [extract] Improve performance, especially on longer reads.
  • [extract] Improve performance with long reads (actually a bug fix)
  • [extract] num_soft_clipped_start and num_soft_clipped_end were incorrect on some reverse-mapped reads